Management of atypical chronic lymphocytic leukemia presenting with extreme leukocytosis
نویسندگان
چکیده
منابع مشابه
Management of chronic lymphocytic leukemia.
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) is usually diagnosed in asymptomatic patients with early-stage disease. The standard management approach is careful observation, irrespective of risk factors unless patients meet the International Workshop on CLL (IWCLL) criteria for "active disease," which requires treatment. The initial standard therapy for most patients combines a...
متن کاملManagement of chronic lymphocytic leukemia.
In the last decade, the management of chronic lymphocytic leukemia has undergone profound changes that have been driven by an improved understanding of the biology of the disease and the approval of several new drugs. Moreover, many novel drugs are currently under evaluation for rapid approval or have been approved by regulatory agencies, further broadening the available therapeutic armamentari...
متن کاملChronic lymphocytic leukemia presenting as purpura fulminans.
A 61-yearold man presented with ecchymoses over his knees and ear lobes. Physical examination on admission reveled an ill-looking man. Multiple areas of ecchymoses were seen over his knees and ear lobes. There were remarkable necrotic areas on the ecchymoses (Figure: 1,2). Other pertinent physical findings inluded an enlarged spleen palpable 5 cm below the left costal margin, multiple palpable ...
متن کاملChronic lymphocytic leukemia presenting with localized gynecologic symptoms.
BACKGROUND Although no cure exists for chronic lymphocytic leukemia (CLL), treatment can reduce morbidity and/or improve survival in advanced disease. Identification of patients in an early disease state allows monitoring and treatment as soon as appropriate. We were unable to find previous reports of early CLL disease presenting with gynecologic symptoms. This report seeks to alert gynecologis...
متن کاملDigital imaging of peripheral blood identifies atypical chronic lymphocytic leukemia.
A 77-year-old woman presented with cervical adenopathy. A complete blood count was performed: white 1 , and ZAP70 1. Cytogenetics/molecular analysis revealed trisomy 12 and unmutated immunoglobulin heavy chain variable region (IgVH). Positron emission tomography computed tomography showed splenomegaly and widespread adenopathy. WBC differential by digital microscopy (Cellavision) revealed 9% ne...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Case Reports
سال: 2020
ISSN: 2050-0904,2050-0904
DOI: 10.1002/ccr3.2773